Iside effects of salicylates (ACK), corticosteroids and imunomodulators on the gastroduodenal mucosa - medication used in rheumatoid arthritis treatment

The aim is to determine pathological -ulcero-erosive changes in the gastroduodenal Wooden Figure mucosa (erosions, ulcers, ulcers, ulcer complications, subepithelial hemorrhage, etc.) resulting from the adverse effects of salicylates /ACK/ corticosteroid, imunoodulatora which was prescribed in the treatment of rheumatoid arthritis (RA).The test was performed on 50 patients diagnosed with RA who were on the two-year continuous therapy.

When respondents were done gastroscopy and pathological macroscopic changes lunch boxes resulting from the gastroduodenal mucosa as a result of adverse effects of administered drugs verified.After two years of preparations ACK controlled therapy, corticosteroids, imunomodula- sector on mucosa gastroduodenal erosions were found in 81.5% of patients, gastric ulcer in 33%, duodenal ulcer with 18.

5% of patients and bleeding in 44.4%.

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